Cutaneous manifestations of rheumatoid arthritis

Authors

  • Prakash B Vydehi institute of medical sciences & research center
  • CA Jayashankar
  • Shivalingappa VM
  • Bhakthavatsalam SA
  • Chandrashekar K

DOI:

https://doi.org/10.15305/ijrci/v3i1/107

Keywords:

rheumatoid arthritis, autoimmune, cutaneous, nevi, striae

Abstract

Rheumatoid arthritis (RA) is a multisystem autoimmune disease, affecting the joints predominantly, and extra-articular sites like skin, lungs, heart etc. The American College of Rheumatology (ACR) in collaboration with the European League Against Rheumatism (EULAR) in 2010, revised the 1987 ACR classification criteria for RA. The criteria covered four areas (joint involvement, serodiagnosis, acute phase reactants, duration of arthritis) and established a point value on a scale of 0 to 10. Patients with a value of 6 or higher are classified as having RA.

Although there are a number of studies on each of these factors, there is a paucity of studies on the cutaneous manifestations in RA patients. The present study explores cutaneous manifestations in RF-positive, predominantly female patients in their fourth decade of age. Drug-induced and other miscellaneous side effects accounted for majority of the lesions. A significant correlation of nevi and striae with RA has been observed in this population.



Author Biography

Prakash B, Vydehi institute of medical sciences & research center

Department of Dermatology, Professor.

References

Jorizzo JL, Greer KE, Callen JP. Miscellaneous disorders with prominent features involving the skin and the joints. Chapter 5. Dermatologic signs of internal disease. Third ed, Saunders. 2003.

Kobelt G, Jonsson L, Lindgren P, Young A, Eberhardt K. Modelling the progression of rheumatoid arthritis: a two-country model to estimate costs and consequences of rheumatoid arthritis. Arthritis Rheum 2002 Sep;46(9):2310-9.

Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Neal S, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/ European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010 Sep;62(9):2569-81.

Yamamoto T. Cutaneous manifestations associated with rheumatoid arthritis. Rheumatol Int 2009 Jul;29(9):979-88.

Chen KR, Toyohara A, Suzuki A, Miyakawa S. Clinical and histopathological spectrum of cutaneous vasculitis in rheumatoid arthritis. Br J Dermatol 2002 Nov;147(5):905-13.

Magro CM, Crowson AN. The spectrum of cutaneous lesions in rheumatoid arthritis: A clinical and pathological study of 43 patients. J Cutan Pathol 2003 Jan;30(1):1-10.

Michel C, Cribier B, Sibilia J, Kuntz JL, Grosshans E. Nail abnormalities in rheumatoid arthritis. Br J Dermatol 1997 Dec;137(6):958-62.

Ruiz-Maldonado R. Measuring congenital melanocytic nevi. Pediatr Dermatol 2004 Mar-Apr;21(2):178-9.

Harris E Jr. Rheumatoid arthritis. Curr Opin Rheumatol 1994 May;6(3):287-9.

Chu P, Connolly MK, LeBoit PE. The histopathologic spectrum of palisaded neutrophilic granulomatous dermatitis in patients with collagen vascular disease. Arch Dermatol 1994 Oct;130(10):1278-83.

Jorizzo JL, Daniels JD. Dermatological conditions reported in patients with rheumatoid arthritis. J Am Acad Dermatol 1983 Apr;8(4):439-57.

Sayah A, English JC. Rheumatoid arthritis: A review of the cutaneous manifestations. J Am Acad Dermatol 2005 Aug;53(2):191-209.

Alikhan A, Ibrahimi OA, Eisen DB. Congenital melanocytic nevi: Where are we now? Part I. Clinical presentation, epidemiology, pathogenesis, histology, malignant transformation, and neurocutaneous melanosis. J Am Acad Dermatol 2012 Oct;67(4):495.e1-17.

Albrecht J, Atzeni F, Baldini C, Bombardieri S, Dalakas MC, Demirkesen C, et al. Skin involvement and outcome measures in systemic autoimmune diseases. Clin Exp Rheumatol 2006 Jan-Feb;24(1 Suppl 40):S52-9.

Downloads

Published

04-02-2015

Issue

Section

Original Articles