The clinical spectrum of Vogt-Koyanagi-Harada syndrome: A single-center experience from South India

Authors

  • Padmamalini Mahendradas Narayana Nethralaya, Super Speciality Eye Hospital and Postgraduate Institute of Ophthalmology, Bangalore
  • Ankush Kawali Narayana Nethralaya
  • Neha Bharti Narayana Nethralaya
  • Dhawal Haria Narayana Nethralaya
  • Naren Shetty Narayana Nethralaya
  • Rohit Shetty Narayana Nethralaya
  • Bhujang K Shetty Narayana Nethralaya

DOI:

https://doi.org/10.15305/ijrci/v1iS1/55

Keywords:

Vogt- Koyanagi- Harada disease, Exudative Retinal Detachment, Sunset glow fundus, Poliosis, Vitiligo, Tinnitus, systemic Steroids, Systemic immunosuppressive therapy

Abstract

Aim

To report the clinical features, investigations, management, and outcome in typical cases of Vogt-Koyanagi-Harada Syndrome (VKH) in a tertiary eye care center in South India.

 

Materials and methods

Retrospective interventional case series of VKH patients.

 

Results

Seventy-one eyes of 36 patients (age range 12-68 years) were included. Anatomical diagnoses were posterior uveitis (15 eyes) and pan uveitis (56 eyes). The classification of the cases with regard to VKH disease was as follows: six eyes were classified as complete, 41 eyes as incomplete, and 24 eyes as probable VKH disease. Commonest extraocular manifestation noted in 25 cases was headache. The more common ocular presentations were disc hyperemia (40 eyes) and exudative retinal detachment in the posterior pole (46 eyes) and in the retinal periphery (24 eyes). All patients were managed on systemic steroids. Systemic immunosuppressive therapy was given in 21 cases. Majority of the participants had good visual outcome.

Conclusion

Early recognition and aggressive treatment of VKH disease result in good visual outcome in typical VKH cases.

Author Biography

Padmamalini Mahendradas, Narayana Nethralaya, Super Speciality Eye Hospital and Postgraduate Institute of Ophthalmology, Bangalore

Department of uveitis and Ocular Immunology

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Published

26-12-2013

Issue

Vol. 1 No. S1 (2013): Observational studies dealing with various aspects of rheumatic diseases

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Original Articles

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