Leprosy mimicking vasculitis
DOI:
https://doi.org/10.15305/ijrci/v6i1/263Keywords:
Leprosy, Vasculitic neuropathies, erythema nodosum, ulcer, mononeuritis multiplexAbstract
Leprosy is a chronic disease primarily involving the peripheral nerves and the skin. Painless skin patches and ulceration in hands and feet are the common clinical presentation of the disease. The present study reports a relatively unusual case of leprosy mimicking vasculitis in a 32-year-old male.
References
Vijayan J, Wilder-Smith EP. Neurological Manifestations of Leprosy [Internet]. International Textbook of Leprosy. 2016 [cited 2018 Mar 27]. Available from: http://www.internationaltextbookofleprosy.org/chapter/neurological-manifestations-leprosy
Smith DS, Kelly EA. Leprosy Clinical Presentation: History, Physical, Causes [Internet]. [cited 2018 Mar 27]. Available from: https://emedicine.medscape.com/article/220455-clinical
Rosenberg RN, Lovelace RE. Mononeuritis Multiplex in Lepromatous Leprosy. Arch Neurol 1968;19(3):310–4.
Misra DP, Parida JR, Chowdhury AC, Pani KC, Kumari N, Krishnani N, et al. Lepra reaction with lucio phenomenon mimicking cutaneous vasculitis. Case Reports Immunol 2014;2014:641989.
Johnston RB. 23 - Bacterial and Rickettsial Infections. In: Weedon’s Skin Pathology Essentials (Second Edition) [Internet]. Elsevier; 2017. p. 404–31. Available from: https://www.sciencedirect.com/science/article/pii/B9780702068300500232
Hussain R, Lucas SB, Kifayet A, Jamil S, Raynes J, Uqaili Z, et al. Clinical and histological discrepancies in diagnosis of ENL reactions classified by assessment of acute phase proteins SAA and CRP. Int J Lepr Other Mycobact Dis 1995;63(2):222–30.
Blaes F. Diagnosis and therapeutic options for peripheral vasculitic neuropathy. Ther Adv Musculoskelet Dis 2015;7(2):45–55.
Mehdi A, Beydoun SR. Vasculitic Neuropathy Clinical Presentation: History, Physical, Causes [Internet]. [cited 2018 Mar 27]. Available from: https://emedicine.medscape.com/article/1172488-clinical
Mehdi A, Beydoun SR. Vasculitic Neuropathy: Background, Pathophysiology, Epidemiology. 2017 Aug 30; Available from: https://emedicine.medscape.com/article/1172488-overview
Suresh E. Diagnostic approach to patients with suspected vasculitis. Postgrad Med J 2006;82(970):483–8.
Kumarasinghe P, Uprety S, Sarkar R. Hypopigmentary disorders in Asian patients. Pigment Int 2017;4:13-20.
Kumar B, Dogra S. Leprosy: A disease with diagnostic and management challenges!. Indian J Dermatol Venereol Leprol 2009;75:111-5
Chauhan S, D’Cruz S, Mohan H, Singh R, Ram J, Sachdev A. Type II lepra reaction: an unusual presentation. Dermatol Online J 2006;12(1):18.
Yamamoto M, Ito Y, Mitsuma N, Hattori N, Sobue G. Pain-related differential expression of NGF, GDNF, IL-6, and their receptors in human vasculitic neuropathies. Intern Med 2003;42(11):1100–3.
Pitta I, Silveira R, Andrade L, Giesel L, Olmo R, Vital R, et al. Demyelination as presentation in leprosy neuropathy (P1.316). Neurology [Internet]. 2017;88(16 Supplement). Available from: http://n.neurology.org/content/88/16_Supplement/P1.316.abstract
Prayson RA, Sedlock DJ. Clinicopathologic study of 43 patients with sural nerve vasculitis. Hum Pathol 2003;34(5):484–90.
Bush OB. C-reactive protein in leprosy. Int J Lepr 1958;26(2):123-6.
Leal AMO, Magalhães PKR, Souza CS, Foss NT. Pituitary-gonadal hormones and interleukin patterns in leprosy. Trop Med Int Health 2006;11(9):1416–21.
Rea TH. Elevated platelet counts and thrombocytosis in erythema nodosum leprosum. Int J Lepr Other Mycobact Dis 2002;70(3):167–73.
Sampaio L, Silva L, Terroso G, Pimenta S, Brandão F, Pinto J, et al. Hansen’s disease mimicking a systemic vasculitis. Acta Reumatol Port 2011;36(1):61–4.
Misra DP, Parida JR, Chowdhury AC, Pani KC, Kumari N, Krishnani N. Lepra reaction with lucio phenomenon mimicking cutaneous vasculitis. Case Reports Immunol. 2014;2014:641989.
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