Burkholderia sepsis mimicking flare of ANCA-associated vasculitis: A rare presentation
DOI:
https://doi.org/10.15305/ijrci/v8i1/335Keywords:
Burkhalderia, ANCA VAsculitis, Sepsis, Biological Therapy, RituximabAbstract
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune condition that primarily targets small to medium sized vessels in multiple organ systems, with sinonasal, pulmonary and renal involvement being common. The present case study discusses a known case of ANCA associated vasculitis, type 2 diabetes and hypertension, who presented with altered sensorium and weakness of the left side of the body. Few months before the onset of symptoms, the patient received rituximab injection for treating cutaneous panniculitis and high pANCA titers. MRI of brain and CECT of chest were suggestive of vasculitis and blood culture showed the growth of Burkholderia cepacia. She was treated with broad spectrum antibiotics and other supportive treatment. Despite all the efforts including ionotropic and ventilator supports, the patient succumbed to the infection.
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