Amyloid arthropathy presenting as symmetrical polyarthritis
DOI:
https://doi.org/10.15305/ijrci/v4i1/181Keywords:
amyloid, polyarthritis, arthropathyAbstract
The present case study deals with two cases of symmetrical polyarthritis mimicking rheumatoid arthritis. Autoantibodies and rheumatoid factor were negative in both the cases and subtle clinical findings led to the diagnosis. The former patient was diagnosed with primary amyloidosis-related arthropathy and the latter with multiple myeloma-related amyloid arthropathy.
References
Duna GF, Cash JM. Rheumatic manifestations of dysproteinemias and lymphoproliferative disorders. Rheum Dis Clin North Am 1996;22:39–51.
Wiernik PH. Amyloid joint disease. Medicine (Baltimore) 1972;51:465–479.
Hickling P, Wilkins M, Newman GR, Pritchard MH,Jessop J, Whittaker J, Nuki G. A study of amyloid arthropathy in multiple myeloma. Q J Med 1981;50:417–433.
Comenzo RL. Primary systemic amyloidosis. Curr Treat Options Oncol 2000;1:83–89.
Kyle RA, Gertz MA. Primary systemic amyloidosis: clinical and laboratory features in 474 cases. Semin Hematol 1995;32:45–59.
Gillmore JD, Lovat LB, Persey MR, Pepys MB, Hawkins PN. Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid Aprotein. Lancet 2001;358:4–5.
Hou FF, Reddan DN, Seng WK, Owen WF Jr. Pathogenesis of beta(2)-microglobulin amyloidosis: role of monocytes/macrophages. Semin Dial 2001;14:135–139
Published
Issue
Section
License
Copyright for articles published in this journal is retained by the authors, with first publication rights granted to the ‘Internet Journal of Rheumatology and Clinical Immunology’. All the published content, except where otherwise noted, is licensed under Creative Commons license (CC-BY).
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) after the publication of the manuscript in IJRCI, as it can lead to productive exchanges, as well as earlier and greater citation of published work.