GAVE: An interesting cause of iron deficiency anemia

Authors

  • Sham Santhanam Madras Medical College
  • M Madeshwaran Madras Medical College
  • S Rajeswari

DOI:

https://doi.org/10.15305/ijrci/v3i1/120

Keywords:

GAVE, Systemic Sclerosis, Argon laser photocoagulation

Abstract

Gastric antral vascular ectasia (GAVE) is a rare cause for chronic severe gastrointestinal bleeding requiring repeated transfusions. We present here the case of 55-year-old female who presented with severe iron deficiency anemia with melena. The disease was further diagnosed as GAVE due to the presence of watermelon stomach on endoscopy with features of limited scleroderma. The patient showed symptomatic improvement on treatment with Argon laser photocoagulation and blood transfusion.

References

Ryder JA, Klotz AP, Kirsner JB. Gastritis with veno capillary ectasia as a source of massive gastric haemorrhage. Gastroenterology. 1953; 24: 118–23.

Jabbari M, Cherry R, Lough JO, et al. Gastric antral vascular ectasia: the watermelon stomach. Gastroenterology. 1984; 87: 1165–70.

Gardiner GW, Murray D, Prokipachuk EJ. Watermelon stomach, or antral gastritis. J Clin Pathol. 1985; 85: 1317–8.

Sebastian S, O’Morain CA, Buckley MJM. Review article: current therapeutic options for gastric antral vascular ectasia. Aliment Pharmacol Ther. 2003 Jul 15;18(2):157–65.

Chawla SK, Ramani K, Loaesti P. The honeycomb stomach: coalesced gastric angiodysplasia. Gastrointest Endosc 1990;36: 516–8.

Ward EM, Raimondo M, Rosser BG, et al. Prevalence and natural history of gastric antral vascular ectasia in patients undergoing orthotopic liver transplantation. J Clin Gastroenterol 2004;38:898–900.

Gostout CJ, Viggiano TR, Ahlquist DA, et al. The clinical and endoscopic spectrum of the watermelon stomach. J Clin Gastroenterol 1992;15:256–263.

Kar P, Mitra S, Resnick JM, Torbey CF. Gastric antral vascular ectasia: case report and review of the literature. Clin Med Res. 2013;11(2):80-85.

Amarapurkar DN, Patel ND. Gastric antral vascular ectasia (GAVE) syndrome. J Assoc Physicians India. 2004;52:756-758.

el-Omar MM, Jenkins AP, Hollowood K, Banerjee AK, Thompson RP. Gastric telangiectasis: a rare cause of severe blood loss in CREST syndrome. Postgrad Med J. 1994;70(822):302-304.

Hung EW, Mayes MD, Sharif R, et al. Gastric antral vascular ectasia and its clinical correlates in patients with early diffuse systemic sclerosis in the SCOT trial. J Rheumatol. 2013;40(4):455-460.

Downloads

Published

09-01-2015

Issue

Section

Case Studies