Internet Journal of Case Reports

Thrombotic microangiopathy in membranous lupus nephritis

2016-08-29T12:21:55+00:00

Renal vascular lesions in SLE are grouped into uncomplicated vascular immune deposits, non-inflammatory necrotizing vasculopathy, thrombotic microangiopathy (TMA) and renal vasculitis. Thrombotic microangiopathy (TMA) is a rare finding in patients with SLE and is associated with poor prognosis. Treatment approach for TMA with membranous nephritis is highly challenging. The present case study discusses the case of a young woman with SLE and membranous lupus nephritis, complicated by TMA.

A case of Darier-Roussy sarcoidosis

2016-08-29T12:21:55+00:00

Subcutaneous sarcoidosis, a rare form of cutaneous sarcoidosis, is seen in approximately 4.3-12.1% of patients with systemic sarcoidosis. These lesions are often associated with less severe systemic disease and usually appear at the beginning of the disease. The present study discusses an unusual case of subcutaneous sarcoidosis with interferon-γ release assay (IGRA) positivity. The case report highlights the increased chances of misdiagnosis of Darier-Roussy sarcoidosis as tuberculosis based on positive IGRA, especially in countries with increased prevalence of TB.

Alveolar soft part sarcoma: A rare cytological impression

2016-08-29T12:21:55+00:00

Alveolar soft part sarcoma (ASPS), a malignant soft tissue tumor with unknown etiology, predominantly occurs in the head and neck region, mainly the tongue and the orbit. The characteristic histopathological feature includes alveolar or pseudoglandular pattern, with PAS-positive, diastase-resistant intra-cytoplasmic inclusions. Primary therapy is total resection and adjuvant chemoradiation therapy. The present case study describes a rare case of ASPS of the anterior chest wall in a 15-year-old patient, diagnosed on fine-needle aspiration cytology. Total resection of the tumor with chemo-radiotherapy was performed and the follow-up after 2 years showed neither local recurrence nor distant metastases.

En coup de sabre

2016-08-29T12:21:56+00:00

En coup de sabre, a variant of linear scleroderma, presents as an indented, vertical, colorless, line of skin on the forehead. The indentation appears as a sabre cut on the forehead. It may be associated with atrophy of muscles underlying bone and rarely the brain tissue. The present patient was ANA positive with a negative profile. Based on the findings, the disease was diagnosed as linear scleroderma.

Ballooning of femoral head in juvenile idiopathic arthritis

2016-08-29T12:21:56+00:00

A 22-year-old female patient with oligoarticular juvenile idiopathic arthritis (JIA) visited the outpatient department with difficulty in walking, climbing stairs and getting up from sitting position. She had pain in both hip and knee joints. On examination, she had no tenderness in both knee and hip joints. However, she had severe restriction of movements at both hip joints in all direction. The X-ray shows diffuse osteoporosis and overgrowth of femoral head compared to the acetabular cavity leading to restriction of hip movements (Fig. 1).